Entity
  • EG 427

    Created in 2019


  • Trend leader (A+)
    Existing signals make this entity one of the most dynamic startups
  • Social networks

    2,066
  • Activities

  • Technologies

  • Entity types

  • Location

    29 Rue du Faubourg Saint-Jacques, 75014 Paris, France

    Paris

    France

  • Employees

    Scale: 11-50

    Estimated: 26

  • Engaged catalyst

    12
    0 0
  • Added in Motherbase

    1 year, 9 months ago
Description
  • Value proposition

    Pinpoint Gene Therapy

    At EG427 our unique, non-replicative Herpes Simplex Virus type 1 (HSV-1) based vector platform called HERMES, delivers, with pinpoint precision, highly selective, durable expression of disease modifying transgenes to address prevalent diseases in neurology.
    Our lead asset EG110A, for the treatment of neurogenic bladder dysfunction, has received IND clearance in June 2024 from the US FDA. Our revolutionary approach to the treatment of this disease aims at providing patients with a comprehensive, long-term solution to their bladder management, through a highly selective molecular biology approach overcoming the drawbacks of current standard of care.

    Our HQ and labs are in Paris, France, where we were founded in 2019. We have raised over USD 21 million, including from our Series A in 2021.

    Gene therapy, peripheral nervous system disorders, neurogenic bladder, HSV-1 vector platform, urinary bladder dysfunction, Herpes type 1 gene therapy platform, and treatment of nervous system disorders

  • Original language

    Pinpoint Gene Therapy

    At EG427 our unique, non-replicative Herpes Simplex Virus type 1 (HSV-1) based vector platform called HERMES, delivers, with pinpoint precision, highly selective, durable expression of disease modifying transgenes to address prevalent diseases in neurology.
    Our lead asset EG110A, for the treatment of neurogenic bladder dysfunction, has received IND clearance in June 2024 from the US FDA. Our revolutionary approach to the treatment of this disease aims at providing patients with a comprehensive, long-term solution to their bladder management, through a highly selective molecular biology approach overcoming the drawbacks of current standard of care.

    Our HQ and labs are in Paris, France, where we were founded in 2019. We have raised over USD 21 million, including from our Series A in 2021.

Catalyst interactions
Catalyst TypeTweets Articles
Gouvernement Gouvernement
Other

11 Apr 2025


Ministère chargé de l'Enseignement supérieur et de la Recherche Ministère chargé de l'Enseignement supérieur et de la Recherche
Government Administration
Other

11 Apr 2025


Ministry of Economy
Ministry of Economy
Government Administration
Ministry of Economy
Government Administration
Other

11 Apr 2025


Medicen Paris Region
Medicen Paris Region
Public business cluster, French Cluster, Civic and Social Organizations
Medicen Paris Region
Public business cluster, French Cluster, Civic and Social Organizations
Other

11 Apr 2025


Région Ile de France
Région Ile de France
National and local authorities, Government Administration
Région Ile de France
National and local authorities, Government Administration
Other

11 Apr 2025


Bpifrance
Bpifrance
Bank, Banking
Bpifrance
Bank, Banking
Other

11 Apr 2025


Toulouse Tech Transfer Toulouse Tech Transfer
Other

8 Mar 2025


Avolta
Avolta
Finance, Investment Banking
Avolta
Finance, Investment Banking
Other

22 Feb 2025


Réseau SATT Réseau SATT
Other

7 Mar 2025


BFM Business
BFM Business
Media, Broadcast Media Production and Distribution
BFM Business
Media, Broadcast Media Production and Distribution
Other

4 Mar 2025


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